Zika Virus Panel (MHD1411)

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*The Centers for Disease Control and Prevention (CDC) updates recommendations for Zika virus testing on a continuing basis. Although the information below is updated regularly, we recommend reviewing the CDC’s website (http://www.cdc.gov/zika/index.html)if you have other questions.


Zika virus testing is used to detect a Zika infection in a person without signs and symptoms and to determine whether a person with signs and symptoms of Zika has been infected after exposure in a region with Zika virus. It may also be used to test people who have had sexual contact with a recent traveler to a country with Zika.

Zika testing is recommended using a blood test and a urine test. Testing should be performed on a blood and a urine sample collected during the first two weeks after symptoms appear. A positive result on any sample suggests a strong likelihood that you have a Zika virus infection and no additional testing may be necessary. A negative result does not exclude Zika virus infection and serum should be analyzed by IgM antibody (serological) testing. This test must be ordered by your physician.

Please note: The CDC testing recommendations for pregnant women are the same for those with ongoing and those with limited risk for possible Zika virus exposure who report clinical illness consistent with Zika virus disease (symptomatic pregnant women). Symptomatic pregnant women who are evaluated less than two weeks after symptom onset should receive serum and urine Zika virus rRT-PCR testing. Symptomatic pregnant women who are evaluated two to 12 weeks after symptom onset should first receive a Zika virus immunoglobulin (IgM) antibody test; if the IgM antibody test result is positive or equivocal (unclear), serum and urine rRT-PCR testing should be performed.

Recommended for:

If you are pregnant and traveled to an area, such as Brazil, where the Zika virus is actively transmitted or had sexual relations with someone who has, then you should be tested. If you had unprotected sexual contact with someone who has traveled to an endemic area and has Zika symptoms you should be tested.

About 80 percent of individuals infected with Zika virus will have no symptoms at all, while others will have only mild illness. For people who develop symptoms, the prognosis is very good for a full recovery. Zika symptoms are similar to other mosquito-borne illnesses like dengue fever and chikungunya. The similarities between Zika symptoms and other diseases mean that laboratory testing is essential to diagnose the Zika virus. The most common initial symptoms of Zika include:

  • Fever
  • Rash
  • Joint pain
  • Conjunctivitis (pink eye) lasting from a few days to a week.

For more information about this test visit Labtestonline.org


  • Zika Virus PCR, Serum
  • Zika Virus PCR, Urine


There is no preparation for this test.

Test Processing:

2-4 days

*Your health is our main concern at HNL Lab Tests Direct (LTD). Interpreting test results can require the expertise of a trained health care provider. LTD recommends consulting with your health care provider whenever possible.

Special Note:

Certain public health agencies require notification when this test is positive.  They use this information to track emerging trends in infectious disease.

Fact Sheet for Pregnant Women:  Understanding Results from the Viracor-IBT Laboratories, Inc.’s Zika Virus Real-time RT-PCR test.

Fact Sheet for Patients: Understanding Results from the Viracor-IBT Laboratories, Inc.’s Zika Virus Real-time RT-PCR test.


The use of this Zika test is authorized by the Food and Drug Administration (FDA) for emergency use based on scientific data.  This test has not been FDA cleared or approved, meaning that the FDA has waived certain requirements normally met by product manufacturers.  This waiver has been granted because there is no “adequate, approved, and available alternative” for the diagnosis of Zika virus infection.   This test has been authorized for the diagnosis of Zika virus infection and not for any other viruses or pathogens.  This test is authorized for use until the authorization is terminated or revoked sooner by the FDA.  The information published by Milestone Health Direct does not represent or suggest that the Zika test offered is safe or effective for the diagnosis of Zika virus infection. 

This testing is for individuals meeting Zika virus clinical criteria (e.g., clinical signs and symptoms associated with Zika virus infection) and/or Zika virus epidemiological criteria (e.g., history of residence in or travel to a geographic region with active Zika transmission at the time of travel or other epidemiologic criteria for which Zika virus testing may be indicated). 

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